INTEGRATED DROPLET-DIGITAL MICROFLUIDICS (ID2M)
The ID2M platform combines hydrodynamic pressure and electrostatic force offered in a three-layer hybrid microfluidics device to control droplets with a single cell. The system can perform on-demand operations on single droplets in channels. These operations consist of on-demand droplet generation through a double T-junction droplet generator, tuning of their volume on-demand, merging and mixing of several droplets to create a serial dilution and sorting encapsulated droplets to multiple channels by a cell trapping system.
- Fine droplet control within channels
- Reduction of experimental reagent volumes
- Elimination of manual intervention
- Single-cell analysis
TRL3 – Experimental proof of concept
Biological and chemical experiments