Bone regeneration products to rebuild bone throughout the body

Induce Biologics Inc. is a regenerative medicine company developing bone regeneration products to rebuild bone throughout the body. The products are intended to be used in the three main markets of surgical bone reconstruction: spine, orthopedics and dental/oral craniofacial.

Forward osmosis technologies for wastewater treatment

Water scarcity and clean water acquisition costs have led to the rapid expansion of desalination or demineralization capacities for the generation of clean water. Low cost high efficiency solutions that produce fresh water from unusable water sources are in high global demand.

Low-dose positron emission mammography (LD-PEM) for breast cancer

Each year, worldwide, more than 2 million women are diagnosed with breast cancer, the second most common cancer in women. Breast cancer accounts for approximately 26% of all cancers diagnosed today.

Scalable vector manufacturing enhancement using viral sensitizers

Oncolytic viruses and adoptive cell therapy (using genetically engineered immune cells) are two highly promising anti-cancer strategies being developed. The manufacture of thesetherapeutics for clinical testing relies on producing viruses from cells, a process that is highly regulated, complex, inefficient, and challenging to implement on a large scale.

A low-cost, portable ultrasound-guided fus system for tumour treatments

The platform will be able to accurately target and treat tumors through advanced phased array technology while monitoring and controlling tissue damage through our proprietary Local Harmonic Motion (LHM) technology or through MRI. The result is the highest throughput, most accurately focused ultrasound system for non-invasive treatment.

A cost-effective, convenient, zero-waste biogas hydrogen sulfide removal technology

The technology is a cost-effective, convenient, zero-waste targeted gas cleaning solution for the growing three billion dollar global problem caused by toxic and corrosive hydrogen sulfide in the renewable natural gas industry. It filters hydrogen sulfide out of renewable natural gas, allowing users to drastically reduce their maintenance costs.

Novel targets and pathways for hematopoiesis and leukemia

Although umbilical cord blood (CB)‐derived hematopoietic stem cells (HSCs) are essential in many lifesaving regenerative therapies, their limited number in CB units has significantly restricted their clinical use and the subsequent advantages they provide during transplantation.

Inhibition of peripheral serotonin for the treatment of metabolic diseases

Obesity and non-alcoholic fatty liver disease (NAFLD) are highly prevalent non-communicable diseases impacting over 30% of adults in Canada and globally. These 2 diseases are important as they are primary risk factors for developing many other chronic diseases including type 2 diabetes (T2D), cardiovascular disease, chronic kidney disease and many cancers.

Dual-action therapies for epilepsy

From the 60M epileptics worldwide, about 30% of them are/will be nonresponsive to all current traditional anti-seizure medication, thus representing a large unmet medical need and a major economic burden. The epilepsy drug market is a large ($4.5B) and growing market (CAGR of 3.8%) to reach $5.5B by 2022.

Targeting RAD51 and BRCA2 for cancer therapy

Cancer cells are inherently unstable. That instability has been exploited as a tumor-selective cancer therapy. Cancer cells depend heavily on mechanisms, including DNA repair, that allow them to survive in the face of accumulated damage to DNA.

A novel solution for control of bleeding

Trauma to the torso (chest, abdomen, pelvis and back) occurs and compression cannot be applied. Non-compressible hemorrhage from truncal injury is the leading cause of potentially survivable deaths of American troops and second leading cause in the civilian setting.

Targeting neuroinflammation for brain health

Inflawell is a proprietary plant extract combined with antioxidants and natural lipids. It is manufactured under GMP and is safe and efficacious. The plant species grows in the Middle East and Africa and has been used over thousands of years as a natural remedy to relieve pain as well as for amnesia.

Resorbable bone tape for CMF(Craniomaxillofacial)fractures

Description of the Invention CMF fractures occur from physical trauma such as vehicular accidents, fights, falls and sports injuries. Following surgical reduction to achieve anatomical alignment and bone union, facial fractures are usually immobilized with between 3 and 5 titanium or PLA/PLGA resorbable mini-plates. Implantation requires drilling into healthy bone and the delicate insertion of

Personalized cancer treatment selection device

Description of the Invention Pear’s technology is based on the combination of microfluidics (body on a chip) and biomaterials (hydrogel mimicking human tumor microenvironment) to recreate the lifecycle of cancer drugs outside a patient’s body. The body on a chip device is used to mimic a drug’s journey through the human body. It contains a

Time Resolved Dynamic Angiographic Computed Tomography (TRD-ACT)

Background The clinical gold standard for assessing the functional significance of a coronary artery stenosis is the invasive fractional flow reserve (FFR) technique, in which a specialized catheter is advanced to the culprit artery with aids of fluoroscopy to measure the flow pressure gradient across a plaque during maximal hyperemia. Recently, noninvasive assessment of FFR

A portable, small, and cheap kidney dialuzer

Background The ratio of supply to demand for kidney organs has always varied widely in any country.There are about 700,000 people in the United States who need or waiting for kidney replacement, but fewer than 20,000 healthy kidneys can be replaced. According to the research, for these patients, hemodialysis equipment is essential for those patents.For

Fully Immersive VR & Haptic Surgical Simulators System

Description of the Invention The next generation of surgeons expect their training experiences to be dynamic, innovative, realistic and customize to multiple procedure/patient specifics. Marion Surgical are working with surgeons from around the globe to build a truly next generation suite of Virtual Reality Surgical Training Simulators. Through Virtual Reality, Marion Surgical enable surgeons to

Novel Human Cell Collection & Transportation Technology

Description of the Invention The company is dedicated in cryopreserving people’s own cells for future personalized regenerative therapeutics and genomic analysis to provide medically relevant foresight into patients’ current and future health. Cells are becoming the most valuable currency in therapeutics fueling advancements in tissue engineering, 3D organ printing, genetic engineering, and stem cell therapy.

A novel material for transdemal drug delivery of multiple small molecule

Description of the Invention Avro Life Science has developed a novel material for transdermal drug delivery of multiple small molecule drugs, across a wide range of therapeutic categories including cardiovascular health, neuroscience, diabetes, consumer health, and more. The TDS (transdermal delivery system) is a drug-in-adhesive patch with a backing film, adhesive layer, and a release

ecommA novel material for transdemal drug delivery of multiple small molecule